Studies have found a significant association between e-cigarette use and asthma exacerbations [72,73,74]
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Understanding the difference between relative and absolute risk is key when looking at harm reduction for smokers
SNP-exposure estimates (for instruments used in our main analysis) from the GWAS conducted on these subsets were used to re-evaluate our MR associations

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Testing our proposed model among classic cigarettes, e-cigarettes and heated tobacco cigarettes users provides the opportunity to identify shared risk factors as well as unique manifestations between users of various smoking-related products